Tuesday, July 29, 2008

Exercise, diet & cholesterol

Abnormal cholesterol metabolism, including low intestinal cholesterol absorption and elevated synthesis, is prevalent in diabetes, obesity, hyperlipidemia, and the metabolic syndrome. Diet-induced weight loss improves cholesterol absorption in these populations, but it is not known if endurance exercise training also improves cholesterol homeostasis. Wilund KR et al (2008) examined this, by measuring circulating levels of campesterol, sitosterol, and lathosterol in 65 sedentary subjects (average age = 59) with at least 1 metabolic syndrome risk factor before and after 6 months of endurance exercise training. Their data indicated that exercise training reduces plasma cholesterol despite increasing cholesterol absorption in subjects with metabolic syndrome risk factors.

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