Clinical features of Warner Syndrome

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Werner syndrome is a rare autosomal recessive disorder characterized by clinical signs of
1. Premature aging,
2. Short stature,
3. Scleroderma-like skin changes,
4. Endocrine abnormalities,
5. Cataracts,
6. Increased incidence of malignancies.
7. Musculoskeletal manifestations: extensive musculoskeletal manifestations including
i. Osteoporosis of the extremities,
ii. Extensive tendinopathy,
iii. Osteomyelitis of the phalanges,
iv. Abundant soft-tissue calcification,
v. And dense ossified soft-tissue masses etc

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